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Aram Heo

 

Aram Heo

Inje University College of Medicine
Haeundae Paik Hospital
South Korea

Abstract Title: Fetal Biometry Measurements in Diabetic Pregnant Women as Predictors of Neonatal Hypoglycemia

Biography:

Aram Heo graduated from medical school in South Korea and is currently a fourth-year resident in the Department of Obstetrics and Gynecology at Haeundae Paik Hospital, Inje University College of Medicine, Republic of Korea.

Research Interest:

Pregnant women with gestational diabetes mellitus (GDM) or pre-existing diabetes mellitus (DM) are at increased risk of prenatal and neonatal complications, including fetal hyperglycemia, hyperinsulinemia, fetal overgrowth, macrosomia, and large-for-gestational-age infants. This study aimed to investigate the association between fetal biometric parameters measured by ultrasound in diabetic pregnancies and neonatal outcomes, particularly neonatal hypoglycemia, compared with normal pregnancies. This retrospective study included singleton pregnancies delivered at ≥37+0 weeks of gestation at Haeundae Paik Hospital between January 2013 and December 2022. Expectant mothers with GDM or pre-existing DM were compared with those with normal pregnancies. Fetal biometric measurements included head circumference (HC), abdominal circumference (AC), the difference between AC and HC (AC−HC), and the HC/AC ratio. Neonatal outcomes analyzed were neonatal intensive care unit (NICU) admission, intubation, acidosis (umbilical artery pH <7.0), and hypoglycemia. Univariate and multivariate logistic regression analyses were performed to identify independent prognostic factors. A total of 473 pregnant women were included, of whom 175 (37.0%) had diabetes and 298 (63.0%) had normal pregnancies. In diabetic mothers, neonatal hypoglycemia was significantly associated with the HC/AC ratio (p = 0.006) and an AC−HC difference greater than −2.5 cm (p = 0.040). In contrast, no significant association between fetal biometric parameters and neonatal hypoglycemia was observed in the normal pregnancy group. Other neonatal outcomes were not significantly correlated with fetal biometry. In conclusion, singleton pregnancies delivered at ≥37 weeks of gestation in diabetic mothers with a greater discrepancy between fetal HC and AC (HC/AC ratio <0.95 or AC−HC ≥2.5 cm) are at increased risk of neonatal hypoglycemia compared with normal pregnancies.